Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico1 Updated August 11 2017 International Nonproprietary Name (INN) / Denominación Común Internacional (DCI) ANALGESICS Opioid analgesics Codeine
Strength / Concentracion
15mg; 30mg (phosphate) 10mg/ml (sulfate or hydrochloride) in 1ml ampoule 10mg/5ml (sulfate or hydrochloride)
Morphine Morphine Morphine
10mg; 30mg; 60mg (sulfate)
ANTI-INFECTIVE MEDICINES Antibacterial Amoxicillin + Clavulanic acid Azithromycin Azithromycin (for Trachoma treatment)
Benzathine benzylpenicillin
Benzylpenicillin
Procaine benzylpenicillin
500mg + 125mg 200mg/5ml 250mg; 500mg (anhydrous) 900 mg benzylpenicillin (=1.2 million IU) in 5mL vial; 1.44 g benzylpenicillin (=2.4 million IU) in 5mL vial 600 mg (=1 million IU) (sodium or potassium salt) in vial; 3 g (=5 million IU) (sodium or potassium salt) in vial 1 g (=1 million IU); 3 g (= 3 million IU) in vial
Doxycycline
100mg (hydrochloride)
Sulfadiazine
500mg
1
Presentation / Forma Farmacéutica
Tablet
Indication(s)/ Indicacion(es)
Analgesic
Injection
Analgesic; Anaesthetic; Preoperative and short procedures
Oral Solution
Analgesic; Palliative care
Tablet (prolonged release)
Analgesic; Palliative care
Tablet Oral Solution Tablet
Antibacterial Antibacterial
Powder for injection
Antibacterial; Syphilis
Powder for injection
Antibacterial; Syphilis
Powder for injection
Antibacterial; Syphilis
Tablet; Capsule Tablet
Ref
Antibacterial; Malaria prophylaxis and treatment Anti-pneumocystosis; Anti-toxoplasmosis
The therapeutic indications presented in this list of medicines appear as published in the 20th World Health Organization Model List of Essential Medicines published March 2017. The Strategic Fund Medicine List does not seek to replace or complement the WHO the Essential Medicine List or Member States national essential medicine lists. As a result, this list should not be utilized as reference for the development of other essential medicine lists or treatment guidelines. - Las indicaciones terapéuticas se presentan con base en la decimonovena Lista de Medicamentos Esenciales de la Organización Mundial de la Salud publicada en Marzo 2017. La Lista de Medicamentos del Fondo Estratégico no supone ninguna complementación o ampliación de la Lista de Medicamentos Esenciales de la OMS o de las listas de medicamentos esenciales nacionales de los Estados Miembros. Consecuenteme nte, esta lista no debería ser utilizada como referencia para la elaboración de listas de medicamentos esenciales o guías de tratamiento. 2 Only used as single dose treatment of genital Chlamydia Trachomatis and of trachoma. - Solamente utilizado en dosis única para el tratamiento de chlamydia trachomatis genital y tracoma.
2
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico Antileprosy med. Clofazimine Dapsone Ofloxacin Antituberculosis med.
50mg; 100mg 25mg; 50mg; 100mg 400mg
Capsule Tablet Tablet
Ethambutol Isoniazid
100mg; 400mg (hydrochloride) 25mg/ml 50mg/5ml
Isoniazid
100mg
Isoniazid Pyrazinamide
300mg 400mg
Pyrazinamide
150mg
Pyrazinamide Rifabutin Rifampicin
30mg/ml 150mg 20mg/ml
Oral Solution Oral Solution Tablet (dispersable) Tablet Tablet Tablet (scored); Tablet (dispersible) Oral Solution Capsule Oral Solution
Rifampicin
150mg; 300 mg
Tablet; Capsule
Rifampicin + Isoniazid
75mg + 50mg
Rifampicin + Isoniazid
60mg + 30mg
Ethambutol
Rifampicin + Isoniazid + Ethambutol
150mg + 75mg ; 300mg + 150mg; 60mg + 60mg; 150mg + 150mg 150mg + 75mg + 275mg
Rifampicin + Isoniazid + Pyrazinamide
75mg + 50mg + 150mg
Rifampicin + Isoniazid + Pyrazinamide
60mg + 30mg + 150mg
Rifampicin + Isoniazid
Rifampicin + Isoniazid + Pyrazinamide Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Rifapentine nd Antiberculosis med. 2 line
150mg + 75mg + 400mg; 150mg + 150mg + 500mg 150mg + 75mg + 400mg + 275mg 150mg
Amikacin
1g (sulfate) in vial
Bedaquiline
100mg
Leprosy
3
Leprosy (second-line)
4
Tablet
Tuberculosis
5
Tuberculosis; Leprosy
Tablet (dispersable) Tablet (dispersable) Tablet Tablet Tablet (dispersable) Tablet (dispersable)
Tuberculosis
Tablet Tablet 6
Tablet Powder for Injection Tablet
Multidrug-resistant tuberculosis (MDR/TB)
3
Medicines used in the treatment of leprosy should never be used except in combination. - Los medicamentos para el tratamiento de lepra siempre deben ser utilizados en combinación. 4 To be used in combination with rifampicin as a second-line therapy for leprosy treatment. - Para ser utilizado en combinación con rifampicina para el tratamiento de segunda línea de la lepra. 5 For use in patient with HIV receiving protease inhibitors. - Para el uso en pacientes con VIH que reciben inhibidores de proteasa. 6
3
For treatment of latent tuberculosis infection only – Para el tratamiento de la tuberculosis latente unicamente.
7
Procurement of this medicine through the Strategic Fund should be limited for use according to WHO recommended M/XDR-TB regimen in patients for whom there are few or no treatments available. Patients receiving this medicine should be monitored for potential adverse events or related toxicities through national pharmacovigilance programs and data from the WHO Programme for International Drug Monitoring (UPPSALA). - La adquisición de este medicamento a través del Fondo Estratégico debe ser limitada para el uso en pacientes con tuberculosis multi y extensivamente resistente (M-XDR TB) en que hay pocos o ningún tratamiento disponibles y usado según el regimen recomendado por la OMS para M-XDR-TB. Los pacientes que reciben este medicamento deben ser controlados para posibles eventos
Page 2 of 12
7
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico Powder for Injection Capsule Capsule Tablet Tablet Tablet Powder for Injection
Capreomycin
0.5g; 1g (sulfate) in vial
Clofazimine Cycloserine Cycloserine Delamanid Ethionamide
50mg; 100mg 250mg 250mg 50mg 125mg ; 250mg
Kanamycin
1g (sulfate) in vial
Levofloxacin
250mg ; 500mg; 750mg
Tablet
Linezolid
600mg
Tablet
7
Linezolid
100mg/5ml
Powder for Oral Solution
7
Moxifloxacin
400mg
Tablet
Protionamide
250mg
Tablet
P-aminosalicylic acid
4g in sachet
P-aminosalicylate sodium (PAS sodium)
100g (60% w/w)
Streptomycin
1g ( sulfate) in vial
Terizidone
250mg
Multidrug-resistant tuberculosis (MDR/TB)
8
Granule Granules Powder for Injection 9
Capsule
Antifungal Amphotericin B
50mg ( sodium deoxycholate or liposomal complex) in vial
Powder for Injection
Antifungal; Anti-Lesihmaniasis
Antivirals Antiretrovirals Abacavir
60mg
Abacavir
300mg
Abacavir + Lamivudine
60mg + 30mg; 120mg + 60mg
Abacavir + Lamivudine Atazanavir Atazanavir Atazanavir + Ritonavir Darunavir Dolutegravir Efavirenz Efavirenz Emtricitabine
600mg + 300mg 100mg 300mg 300mg + 100mg 75mg; 150mg; 400mg; 600mg; 800mg 50mg 200mg 600mg 200mg
Tablet (dispersible, scored) Tablet Tablet (dispersible, scored) Tablet Capsule Capsule Tablet
HIV/AIDS
10
Tablet Tablet Tablet (scored) Tablet Capsule
adversos o efectos tóxicos relacionados al medicamento a través de programas nacionales de farmacovigilancia y datos del Programa de la OMS para la Vigilancia Farmacéutica Internacional (UPPSALA). 8 Protionamide may be an alternative to ethionamide. La protionamida puede ser utilizada como alternativa a la etionamida. 9
Terizidone may be an alternative to cycloserine. La terizidona puede ser utilizada como alternativa a la cicloserina.
10
Age restriction > 3 years old. Restricción de edad > 3 años de edad.
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Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico Etravirine Lamivudine Lamivudine
100mg; 200mg 150mg 10mg/ml
Lamivudine + Zidovudine
30mg +60mg
Lamivudine + Zidovudine
150mg+300mg 100mg + 25mg; 200mg + 50mg
Lopinavir + Ritonavir Lopinavir + Ritonavir
40mg + 10mg
Lopinavir + Ritonavir Nevirapine
80mg+20mg/ml 200mg
Nevirapine
50mg
Nevirapine
50mg/5ml (100ml)
Ritonavir
25mg
Ritonavir
100mg
Ritonavir
400mg/ 5mL (240ml)
Raltegravir
25mg; 100mg
Raltegravir Tenofovir Tenofovir Tenofovir + Emtricitabine Tenofovir + Emtricitabine + Efavirenz Tenofovir + Lamivudine Tenofovir + Lamivudine + Efavirenz Zidovudine
400mg 300mg 200mg 300mg + 200mg 300mg + 200mg + 600mg 300mg + 300mg 300mg + 300mg + 600mg 300mg
Zidovudine
60mg
Zidovudine
50mg/5ml (100ml)
Zidovudine
10mg/ml in 20ml vial
Zidovudine + Lamivudine + Nevirapine
60mg + 30mg + 50mg
Zidovudine + Lamivudine + Nevirapine Other Antivirals
300mg + 150mg + 200mg
Acyclovir
250mg ( sodium salt) in vial
Acyclovir
200mg
Tablet Tablet Oral Solution Tablet (dispersible, scored) Tablet Tablet (heat stable) Oral pellets (heat stable) Oral Solution Tablet Tablet (dispersible, scored) Oral Solution Tablet (heat stable) Tablet (heat stable) Oral solution Tablet (chewable) Tablet Tablet Tablet Tablet Tablet Capsule Tablet Tablet Tablet (dispersible, scored) Oral Solution Solution for IV Infusion Injection Tablet (dispersible, scored) Tablet Powder for Injection Tablet
11
HIV/AIDS 11 11
Herpes Virus
11
Procurement of this medicine through the Strategic Fund should be limited for use as third-line therapy in treatment-experienced HIV adults who failed second-line antiretroviral therapy. It is recommended patients receiving HIV/AIDS regimens including this medicine be monitored for potential adverse events or related toxicities through national pharmacovigilance programs and data from the WHO Programme for International Drug Monitoring (UPPSALA). - La adquisición de este medicamento a través del Fondo Estratégico debe ser limitada para su uso como tratamiento de tercera línea en adultos con VIH tratados previamente que reprobaron la terapia antirretroviral de segunda línea. Se recomienda que los pacientes que reciben regímenes de VIH / SIDA que incluyen este medicamento ser monitorizados para detectar posibles eventos adversos o efectos tóxicos relacionados al medicamento a través de los programas nacionales de farmacovigilancia y los datos del Programa de la OMS para la Vigilancia Farmacéutica Internacional (UPPSALA).
Page 4 of 12
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico Oseltamivir
75mg (phosphate)
Oseltamivir
12mg/ml
Anti hepatitis medicines Medicines for Hepatitis B Entecavir Entecavir Tenofovir disoproxil fumarate 13 Medicines for Hepatitis C Daclastavir Dasabuvir Ledipasvir + Sofosbuvir Ombitasvir + Paritaprevir + Ritonavir Simeprevir Sofosbuvir Sofosbuvir + Velpatasvir Antiprotozoal medicines Antileishmaniasis medicines Meglumine antimoniate Amphotericin B Miltefosine
0.05mg/ml 0.5mg; 1mg 300mg 30mg; 60mg 250mg 90mg + 400mg 12.5mg + 75mg + 50mg 150mg 400mg 400mg + 100mg
1.5g/ 5 ml (81 mg/ml) in 5ml ampoule 50mg (sodium deoxycholate or liposomal complex) in vial 10mg; 50 mg
Paromomycin
750mg of paromomycin base (sulfate)
Pentamidine
300mg (isethionate)
Capsule Powder for Oral Solution
Influenza Virus (in compliance with WHO treatement guidelines)
Oral Solution Tablet Tablet
Chronic Hepatitis B
Tablet Tablet Tablet Tablet Capsule Tablet Tablet
Chronic Hepatitis C
Injection
Leishmanaiasis
12
Powder for Injection Tablet Solution for Intramuscular Injection Powder for injection
Leishmanaiasis
Leishmaniasis
14
Anti-malarial Amodiaquine Artemether Artemether + Lumefantrine Artesunate
153 mg; 200 mg (hydrochloride) 80 mg/ml 1 ml ampoule 20 mg + 120 mg 60 mg (anhydrous artesunic acid)
Artesunate
50 mg; 200mg
Artesunate + Mefloquine
100 mg + 220mg
Oily Injection Tablet
Malaria treatment to be used in combination with artesunate for P. falciparum. Severe malaria Malaria treatment
Injection
Severe malaria
Tablet
Rectal Dosage Form Tablet
Severe malaria Malaria treatment
12
According to the 20th World Health Organization Model List of Essential Medicines published in March 2017, Oseltamivir is indicated for severe illness fue to confirmed or suspected influenza virus infection in critically ill hospitalized patients. - De acuerdo con la vigésima Lista Modelo de Medicamentos Esenciales de la Organización Mundial de la Salud publicada en marzo de 2017 Oseltamivir, el uso del oseltamivir es indicado solo en casos confirmados o sospechados de influenza viral en pacientes hospitalizados y en situación de enfermedad critica. (WHO 20th EML 2017) 13 According to the 20th World Health Organization Model List of Essential Medicines published in March 2017 and based on current evidences, medicines of this class act as direct antiviral medicines and are included as essential medicines for treatment of hepatitis C virus infection. WHO guidelines recommend specific combinations therapies utilizing medicines from different classes. - De acuerdo con la vigésima Lista Modelo de Medicamentos Esenciales de la Organización Mundial de la Salud publicada en marzo de 2017 y basándose en la evidencia actual, los medicamentos en esta categoría funcionan como antivirales de acción directa y se incluyen como medicamentos esenciales para el tratamiento de la infección por el virus de la hepatitis C. Las guías de la OMS recomiendan combinaciones terapéuticas específicas con medicamentos de diferentes clases. (WHO 20th EML 2017) 14 This medicine should be used in accordance to the recommendations outlined in the Leishmaniasis in the Americas: Recommendations for the treatment (2013) guide. - Este medicamento debe utilizarse en acuerdo con las recomendaciones formuladas en la guía Leishmaniasis en las Américas: Recomendaciones para el tratamiento (2013). 15 Product may be co-packaged with 1 ampoule of 5% sodium bicarbonate solution and 1 ampoule of sodium chloride solution. Producto puede ser presentado en conjunto con 1 ampolla de solución de bicarbonato sódico y 1 ampolla de solución de cloruro de sodio.
Page 5 of 12
15
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico
Artesunate + Amodiaquine
Atovaquone + Proguanil Atovaquone + Proguanil Chloroquine Chloroquine
25 mg + 67.5 mg (hydrochloride); 50 mg + 135 mg (hydrochloride); 100 mg + 270 mg (hydrochloride) 250+100 mg (hydrochloride) 62.5+25 mg (hydrochloride) 50 mg (phosphate or sulfate)/5 ml 100 mg; 150 mg (phosphate or sulfate)
Tablet
Tablet (adult) Tablet (pediatric)
Malaria prophylaxis and treatment Tablet
250 mg (hydrochloride)
Tablet
Dihydroartemisinina + Piperaquina
40 mg + 320 mg
Tablet
Primaquine
5mg; 7.5 mg ; 15 mg (diphosphate)
Tablet
Quinine Sulfadoxine + Pyrimethamine
300 mg quinine hydrochloride/ml in 2ml ampoule 300 mg (quinine sulfate or bisulfate) 500 mg + 25 mg
Antipneumocystosis and antitoxoplasmosis medicines Pyrimethamine 25mg 80mg + 16mg/ml in 5ml or Sulfamethoxazole + Trimethoprim 10ml ampoule Pentamidine 200mg; 300mg Antitrypanosomal medicines 12.5 mg Benznidazole 50 mg 100mg
Malaria prophylaxis and treatment
Oral Solution
Mefloquine
Quinine
Malaria treatment
Malaria prophylaxis; Malaria treatment to be used in combination with artesunate for P. falciparum Malaria treatment As complement to malaria treatment (for radical cure of P.vivax and P.ovale and as gametocytocide for P. falciparum)
Injection
Severe malaria
Tablet
Malaria treatment
Tablet
Malaria treatment to be used in combination with artesunate for P. falciparum
Tablet Injection
Pneumocystis; Toxoplasmosis
Tablet Tablet Tablet (scored) Tablet
American Trypanosomiasis
120mg
Tablet
African Trypanosomiasis (2nd stage); American Trypanosomiasis
Albendazole
400mg
Tablet (chewable)
Intestinal Anthelminthic; AntiFilarial
Ivermectin
3mg
Tablet (scored)
Strongyloidiasis Intestinal anthelminthic Intestinal anthelminthic (for use when praziquantel fails) Anticestodes
Nifurtimox Anthelminthics Intestinal anthelminthics
Mebendazole
500mg
Tablet (chewable)
Niclosamide
500mg
Tablet (chewable)
Page 6 of 12
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico Praziquantel
150mg; 600mg
Tablet
Intestinal anthelminthic;
Praziquantel
600mg
Tablet
Antischistosomal; Antitrematode; Anticestode
Tablet
Antitischistosomal; Antitrematode
Antischistosomals and Antitrematode Medicines Triclabendazole
250mg
Antifilarials 50mg; 100mg Tablet (dihydrogen citrate) ANTINEOPLASTIC, IMMUNOSUPPRESSIVES AND MED. USED IN PALLIATIVE CARE Immunosuppressive Agents Dietylcarbamazine
Filariasis
Powder for Injection
Immunosuppressive
50mg
Tablet
DMARD
Cyclosporine
25mg
Capsule
Cyclosporine
50mg/ml in 1ml ampoule
Injection
250 mg
Capsules
500 mg
Tablets Capsules (immediate release)
Azathioprine
100mg (sodium salt) in vial
Azathioprine
Mycophenolate Mofetil
Tacrolimus
0.5, 1, 5 mg
Immunosuppressive Prophylaxis of organ rejection in adult patients receiving allogeneic renal transplants Prophylaxis of organ rejection in adult patients receiving allogeneic renal or hepatic transplants
Cytotoxic medicines Asparaginase
10,000 IU in vial
Bleomycin
15mg (sulfate) in vial
Calcium folinate
3mg/ml in 10ml ampoule
Calcium folinate
15mg
Carboplatin
150mg; 450mg
Chlorambucil
2mg
Cisplatin
10mg; 50mg
Cyclophosphamide
500mg in vial
Cyclophosphamide
25mg
Cytarabine
100mg in vial
Dacarbazine
100mg in vial
Dactinomycin
500µg in vial
Daunorubicin
50mg (hydrochloride) in vial
Docetaxel
20mg/ml 10mg; 50mg (hydrochloride) in vial 100mg 20mg/ml in 5ml ampoule 50mg/ml in ampoule
Doxorubicin Etoposide Etoposide Fluorouracil
Powder for Injection Powder for Injection Injection Tablet Powder for Injection Tablet Powder for Injection Powder for Injection Tablet Powder for Injection Powder for Injection Powder for Injection Powder for Injection Injection Powder for Injection Capsule Injection Injection
Cytotoxic Agent
Adjuvant Medicine Cytotoxic and Adjuvant Medicine Cytotoxic Agent Cytotoxic and Adjuvant Medicine Cytotoxic Agent
Cytotoxic Agent
Cytotoxic and Adjuvant Medicine Cytotoxic Agent Cytotoxic and Adjuvant Medicine Page 7 of 12
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico
Ifosfamide
1g vial
Mercaptopurine Mesna (2-mercaptoethane sulfonate sodium)
50mg 100mg/ml in 4ml and 10ml ampoules
Methotrexate
50mg (sodium salt) in vial
Methotrexate
2.5mg (sodium salt)
Paclitaxel
6mg/ml
Procarbazine Tamoxifen
50mg (hydrochloride) 10mg; 20mg (citrate)
Trastuzumab
150 & 440 mg
Vinblastine
10mg (sulfate) in vial
Vincristine
1mg; 5mg (sulfate) in vial
Powder for Injection Tablet
Cytotoxic and Adjuvant Medicine Cytotoxic Agent
Injection
Adjuvant Medicine
Powder for Injection
Cytotoxic Agent
Tablet
Cytotoxic Agent; DMARD
Powder for Injection Capsule Tablet Powder for injection Powder for Injection Powder for Injection
Cytotoxic and Adjuvant Medicine Cytotoxic Agent Hormone/Anti-Hormone HER2+ early breast cancer
Cytotoxic Agent
BLOOD PRODUCTS AND PLASMA SUBSTITUTES Plasma fractions for specific use Human normal immunoglobulin
16% protein solution
Human normal immunoglobulin
5% protein solution; 10% protein solution
Coagulation factor VIII
500UI/vial
Coagulation factor IX
500UI/vial; 1000UI/vial
Injection for Intramuscular Administration Injection for Intravenous Administration Powder for injection Powder for injection
16
Plasma fractions for specific use 17
Blood coagulation factors
IMMUNOBIOLOGICS Sera and immunoglobulins anti-D immunoglobulin (human)
250µg in single-dose vial
Injection
Prevention of newborn hemolytic illnesses; Rh negative populations (prophylaxis)
Tablet
Antihypertensive
Tablet
Antihypertensive; Antianginal; Antiarrhythmic; Medicines used in heart failure Hypertension in adults Antihypertensive; Medicines used in heart failure
CARDIOVASCULAR MEDICINES Antihypertensive medicines Amlodipine Bisoprolol Carvedilol Chlorthalidone Enalapril Hydralazine Hydralazine
16
5mg (maleate, mesylate or besylate) 1.25mg; 5mg 3.125mg; 6.25mg; 12.5mg; 25mg; 50mg 12.5mh; 25mg 2.5mg; 5mg (hydrogen maleate) 20mg (hydrochloride) in ampoule 25mg; 50mg
Tablet Tablet Tablet Powder for Injection Tablet
Hypertension
Indicated for primary immune deficiency. - Indicado para deficiencia inmune primaria.
17
Indicated for primary immune deficiency and Kawasaki disease. - Indicado para deficiencia inmune primaria y enfermedad de Kawasaki. 18 Metoprolol and carvedilol as alternatives. - Alternativos: metoprolol y carvedilol. Page 8 of 12
18
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico
(hydrochloride) Hydrochlorothiazide
12.5mg; 25mg
Tablet
Losartan Methyldopa
25mg; 50mg; 100mg 250 mg
Tablets Tablet
Metoprolol
100mg
Tablet
Sodium nitroprusside
50mg in ampoule
Surfactant (Surfactante pulmonar exogeno)
25mg/ml; 80mg/ml
Powder for Infusion Suspension for Intratracheal Instillation
Antihypertensive; Medicines used in heart failure; Diuretics Hypertension in adults Antihypertensive Antihypertensive; Antianginal; Antiarrhythmic; Medicines used in heart failure Hypertension Neonatal care
Antiarrhythmic medicines 100 mg; 200 mg; 400 mg (hydrochloride) 50 mg (hydrochloride)/ mL in 3‐ mL ampoule 250 micrograms/ml in 2‐ml ampoule
Amiodarone
Digoxin
62.5 micrograms; 250 micrograms 50 micrograms/ml 20 mg (hydrochloride)/ml in 5‐ml ampoule 2.5 mg (hydrochloride)/ml in 2‐ml ampoule 40 mg; 80 mg (hydrochloride)
Lidocaine
Verapamil
Tablet Antiarrythmic Injection Injection Tablet
Antiarrythmic Medicines used in heart failure
Oral Solution Injection Injection
Antiarrythmic
Tablet
Antiarrythmic Antianginal medicines
Diuretics Spironolactone Antianginal medicines
25mg
Tablet
Diuretic
Glyceryl trinitrate
500µg
Tablet (sublingual)
Angina
Tablet
Prevention of atherothrombotic events in adults with non-ST segment elevation acute coronary syndrome
Powder for Injection
Thrombosis
Tablet
Lipid-Lowering Agents
Antithrombotic medicines Clopidogrel
75 mg
Streptokinase
1.5million IU in vial
Lipid-lowering agents Simvastatin DIAGNOSTIC AGENTS Radiocontrast media
5mg; 10mg; 20mg; 40mg
19
Losartan can be used as an alternative for treatment of adults with hypertension for those patients in whom ACEi are indicated but not tolerated, specifically due to the presence of adverse events (mainly cough); including the sub-population of hypertensive patients associated with type II diabetes with proteinuria. - Losartan puede ser utilizado como una alternativa para el tratamiento de hipertensión en adultos, para aquellos pacientes en los cuales los IECA están indicados pero no se toleran, específicamente debido a la presencia de eventos adversos (principalmente la tos); incluyendo la sub-población de pacientes hipertensos con asociación de diabetes tipo II con proteinuria. 20 Methyldopa is listed for use only in the management of pregnancy‐induced hypertension. Its use in the treatment of essential hypertension is not recommended in view of the evidence of greater efficacy and safety of other medicines (WHO 20th EML). - Metildopa se lista sólo para su uso en el manejo de la hipertensión inducida por el embarazo. Su uso en el tratamiento de la hipertensión esencial no se recomienda basado en la evidencia de una mayor eficacia y seguridad de otros medicamentos (20a LME OMS). Page 9 of 12
19 20
Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico
Amidotrizoate HORMONES, ENDOCRINE MED. Contraceptives Oral hormonal contraceptives Ethinylestradiol + levonorgestrel Ethinylestradiol + norethisterone Levonorgestrel Injectable hormonal contraceptives Medroxyprogesterone acetate Medroxyprogesterone acetate + estradiol cypionate Norethisterone enantate Insulins and other antidiabetic agents Insulin soluble
Intermediate-acting insulin Glibenclamide Metformin MEDICINES AFFECTING THE BLOOD Antianaemia medicines Recombinant Human Erythropoietin Recombinant Human Erythropoietin Medicines affecting coagulation
140mg to 420mg iodine (sodium or Meglumine salt)/ml in 20ml ampoule
30µg + 150µg 35µg + 1.0mg 30µg; 750µg (pack of two); 1.5mg 150mg/ml in 1ml vial. 25mg + 5mg 200mg/ml in 1ml ampoule 40 IU/ml; 100 IU/ml in 10ml vial 40 IU/ml; 100 IU/ml in 10ml vial (coumpound insulin zinc suspension or isophane insulin) 2.5mg; 5mg 500mg (hydrochloride)
2,000-5,000 UI/ml 20,000-50,000 UI/ml
0.5mg; 1mg; 2mg; 5mg (sodium salt) ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS Warfarin
Dexamethasone Dexamethasone
4mg/ml in 1ml ampoule (disodium phosphate salt)
Injection
Radiocontrast Media
Tablet Tablet
Contraception
Tablet
Contraception
Depot Injection Injection Oily Injection
Contraception Contraception
Injection
Injection
Diabetes
Tablet Tablet
Injection Injection
Anemia
Tablet
Anticoagulant
Injection
2 mg Tablet 100mg (sodium succinate) in Powder for Hydrocortisone vial Injection MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE INHIBITORS Powder for Vecuronium 10mg (bromide) in vial Injection OXYTOCICS AND ANTIOXYTOCICS Oxytocics Oxytocin 10 UI in 1 ml ampoule Injection 200µg (hydrogen maleate) in Ergometrine Injection 1ml ampoule Mifepristone – Misoprostol 200mg - 200µg Tablets Misoprostol 200µg Tablet ANTICONVULSANT AND ANTIEPILEPTIC 25mg; 50mg; 100mg Phenytoin Capsule (sodium salt) 50mg/ml (sodium salt) in Phenytoin Injection 5ml vial
Antiemetic; Anti-allergic /Anaphylaxis; Cytotoxic; Palliative care Palliative care Anaphylaxis; Cytotoxic Muscle Relaxant
Oxytocic Oxytocic
Anticonvulsant; Antiepileptic
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Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico
Phenytoin
Phenobarbital Phenobarbital Carbamazepine
25mg/5 ml; 30mg/5 ml 50mg/ml in 5ml vial (sodium salt) 15mg/5 ml 15mg; 100mg 100mg/5 ml
Carbamazepine
100mg; 200mg
Carbamazepine
100mg; 200mg
Phenobarbital
Diazepam Magnesium sulfate
5mg/ml in 0.5ml; 2ml; 4ml tubes 500mg/ml in 2ml or 10ml ampoule 200mg; 500mg (sodium valproate)
Valproic acid
100mg 200mg/5ml 100mg/ml in 4ml ampoule; 100mg/ ml in 10ml ampoule
Oral Solution Injection Oral Solution Tablet Oral Solution Tablet (chewable)
Anticonvulsant; Antiepileptic
Tablet (scored) Gel or; Rectal solution Injection Tablet (entericcoated) Tablet (crushable) Oral solution
Anticonvulsant; Antiepileptic Medicine used in bipolar disorders Anticonvulsant; Antiepileptic
Injection
PSYCHOTHERAPEUTIC MEDICINES
Haloperidol
25mg (hydrochloride)/ml in 2ml ampoule. 25mg (hydrochloride)/5 ml 100mg (hydrochloride) 25mg (decanoate or enantate) in 1ml ampoule 5mg in 1ml ampoule
Haloperidol
2mg; 5mg
Tablet
10mg; 25mg (hydrochloride)
Tablet
Chlorpromazine Chlorpromazine Chlorpromazine Fluphenazine
Injection Oral Solution Tablet
Psychotic Disorders
Injection Injection
Medicines used in mood disorders Amitriptyline
Fluoxetine 20mg (hydrochloride) Fluoxetine 20mg (hydrochloride) Medicines used in bipolar disorders Lithium carbonate 300mg Lithium carbonate 300mg Medicines used for disorders due to psychoactive substance use Nicotine replacement therapy (gums) 2mg; 4mg (as polacrilex) Nicotine replacement therapy (patch)
5mg to 30mg/16 h; 7mg to 21mg/24h
Capsule Tablet
Palliative Care; Depressive Disorders Palliative Care; Depressive Disorders
Capsule Tablet
Bipolar Disorder
Gums Transdermal patch
Tobacco cessation
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Treatment with 10mg should be utilized only in palliative care. - Tratamiento con 10mg solo debería ser utilizado en cuidados paliativos. Page 11 of 12
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Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico
ANTIPARKINSONISM MEDICINES Biperiden Biperiden GASTROINTESTINAL MEDICINES Antiulcer Medicines Omeprazole
5mg (lactate) in 1ml ampoule 2mg (hydrochloride)
20 mg; 40 mg 10 mg; 20 mg; 40 mg
25 mg/ml (as hydrochloride) in 2-ml ampoule Ranitidine 150 mg (as hydrochloride) 75 mg/5 ml (as hydrochloride) MEDICINES ACTING ON THE RESPIRATORY TRACT Antiasthmatic and medicines for chronic obstructive pulmonary disease
Beclometasone
Ipratropium bromide
Salbutamol
50 micrograms (dipropionate) per dose; 100 micrograms (dipropionate) per dose (as CFC free forms) 20 micrograms/metered dose 100 micrograms (as sulfate) per dose 50 micrograms (as sulfate)/ml 100 micrograms (as sulfate) per dose 5 mg (as sulfate)/ml
Injection
Parkinson’s Disease
Tablet
Powder for oral liquid in Sachets Solid oral dosage form Injection
Antiulcer medicines
Tablet Oral Solution
Inhalation (aerosol) Inhalation (aerosol) Inhalation (aerosol) Injection in 5‐ml ampoule Metered dose inhaler (aerosol) Respirator solution for use in nebulizers
Antiasthmatic Medicines used for chronic obstructive pulmonary disease (COPD)
OTHERS Calcium gluconate
100mg/ml in 10ml ampoule
Injection
Specific Use Antidotes and Others Substances Used in Poisoning; Vitamins and Minerals
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